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姓名 要點  

余權航 教授


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學歷 要點

學校 科系所
台灣大學                                                                臨床牙醫學研究所博士

經歷 要點

工作單位 職稱






研究方向 要點

►口腔胚胎及組織學 ►口腔病理學 ►口腔診斷學


研究計畫 要點



Program Name



Studies on the Chemoprevention, Novel Therapy, and Pathogenesis of Oral Precancer Lesions and Oral Cancer


胺基酮戊酸(ALA)光動力療法於癌源幹細胞特性、化療敏感性、及作為輔助性口腔癌新穎治療法之轉譯醫學研究 Translational Research of Photodynamic Therapy with 5-aminolevulinic acid (ALA) in Cancer Initiating Stemness Property, Chemosensitivity, and Development ALA as Adjuvant Therapy for Oral Cancer


光動力療法提升牙髓幹細胞成骨及脂肪分化潛能之分子機轉探討及應用 Signaling mechanism and application of photodynamic therapy-induced osteogenic and adipogenic differentiation potentials of dental pulp stem cell


奈米化光動力療法標靶口腔癌幹細胞之轉譯研究 Translational investigation of nanoparticle-mediated photodynamic therapy (PDT) on targeting oral cancer stem cells



Elucidation of the mechanisms by which photodynamic therapy-mediated microRNAs involve in the pathogenesis of oral cancer and precancerous lesions and their potentials in clinical application






1).Chou MY, Hu FW, Yu CH, Yu CC. Sox2 expression involvement in the oncogenicity and radiochemoresistance of oral cancer stem cells. Oral Oncol, (in press) (SCI) .

2).Chen HM, Cheng SJ, Lin HP, Yu CH, Wu YC, Chiang CP. Cryogun cryotherapy for oral leukoplakia and adjacent melanosis lesions. J Oral Pathol Med, (in press) (SCI).

3).Ho CM, Hu FW, Lee SS, Shieh TM, Yu CH, Lin SS, Yu CC. ZEB1 as an indicator of tumor recurrence for areca quid chewing-associated oral squamous cell carcinomas. J Oral Pathol Med, (in press) (SCI).

4).Wu YT, Yu CH*. 到宅牙醫醫療。 J Family Dent, 2014; 8(4): 4-8. (review article, corresponding author)

5).Yu CH*, Yu CC. Photodynamic therapy with 5-aminolevulinic acid (ALA) impairs tumor initiating and chemo-resistance property in head and neck cancer-derived cancer stem cells. PLoS ONE, 2014; 9(1): e87129. (first and corresponding author) (SCI), Jan.

6).Huang CE, Hu FW, Yu CH, Tsai LL, Lee TH, Chou MY, Yu CC. Concurrent expression of Oct4 and Nanog maintains mesenchymal stem-like property of human dental pulp cells. Int J Mol Sci, 2014; 15(10): 18623-18639. (SCI), Oct.

7).Tsai LL, Hu FW, Lee SS, Yu CH, Yu CC, Chang YC. Oct4 mediates tumor initiating properties in oral squamous cell carcinomas through the regulation of epithelial-mesenchymal transition. PLoS ONE, 2014; 9(1): e87207 (SCI), Jan.

8).Chang YC, Yu CH*. Successful treatment of oral verrucous hyperplasia with photodynamic therapy combined with cryotherapy – report of 3 cases. Photodiagnosis Photodyn Ther. 2014; 11(2): 127-129. (SCI), Jun.

9).Yu CH, Lin HP, Cheng SJ, Sun A, Chen HM. Cryotherapy for oral precancers and cancers. J Formos Med Assoc, 2014; 113(5): 272-277. (review article) (SCI), May.

10).Wu YT, Yu CH*. Successful treatment of oral verrucous hyperplasia with cryotherapy – a case report. J Family Dent, (corresponding author, accepted) (case report)

11).Yu CH, Chang YC. Clinical efficacy of the Er:YAG laser treatment on hypersensitive dentin. J Formos Med Assoc, 2014; 113(6): 388-391. (short communication, SCI), Jun.

12).Huang YF, Lin JC, Yang HW, Lee YH, Yu CH*. Clinical effectiveness of laser acupuncture in the treatment of temporomandibular joint disorder. J Formos Med Assoc, 2014; 113(8): 535-539. (corresponding author, in press) (SCI), Aug.

13).Peng CY, Huang YF, Lu MY, Lee YH, Yu CH*. Intraosseous verrucous carcinoma arising from an infected dentigerous cyst – a case report. J Formos Med Assoc, (corresponding author, in press) (case report, SCI)

14).Wu YT, Peng CY, Yu CH*. Intraosseous mucoepidermoid carcinoma of the mandible – a case report. J Family Dent, 2013; 8(2): 43-48, Sep.

15).Yu CC, Tsai LL, Wang ML, Yu CH, Lo WL, Chang YC, Chiou GY, Chou MY, Chiou SH. miR415 targets the SOX9/ADAM17 axis to inhibit tumor initiating cells and IL-6-mediated paracrine effects in head and neck cancer. Cancer Research, 2013; 73(11): 3425-3440. (co-second author) (SCI), June.

16).Chang YC, Yu CH*. Successful treatment of a large oral verrucous hyperplasia with photodynamic therapy combined with cryotherapy - a case report. J Dent Sci, 2013; 8(1): 87-90. (corresponding author) (case report, SCI), March.

17).Yu CH, Chen HM, Lin HP, Chiang CP. Expression of Bak and Bak/Mcl-1 ratio can predict photodynamic therapy outcome for oral verrucous hyperplasia and leukoplakia. J Oral Pathol Med, 2013; 42(3): 257-262. (SCI), March.

18).Chu PY, Hu FW, Yu CC, Tsai LL, Yu CH, Wu BC, Chen YW, Huang PI, Lo WL. Epithelial-mesenchymal transition transcription factor ZEB1/ZEB2 co-expression predicts poor prognosis and maintains tumor-initiating properties in head and neck cancer. Oral Oncol, 2013; 49(1): 34-41. (SCI), Jan.

19).Chen HM, Yu CH, Lin HP, Cheng SJ, Chiang CP. 5-Aminolevulinic acid-mediated photodynamic therapy for oral cancers and precancers. J Dent Sci, 2012; 7(4): 307-315. (review article, SCI), Dec.

20).Lin HP, Chen HM, Cheng SJ, Yu CH, Chiang CP. Cryogun cryotherapy for oral leukoplakia. Head Neck, 2012; 34(9): 1306-1311. (SCI), Sep.

21).Hu FW, Tsai LL, Yu CH, Chen PN, Yu CC. Impairment of tumor initiating stem-like property and reversal of epithelial-mesenchymal transdifferentiation in head and neck cancer by resveratrol treatment. Mol Nutr Food Res, 2012; 56(8): 1247-1258. (SCI), Aug.