|
研究成果 
|
研究計畫
|
年度
|
研究名稱
|
擔任
工作
|
補助
金額
|
補助
單位
|
|
99
|
農藥暴露、MDR1基因多形性與粒線體DNA傷害
|
共同主持人
|
355,100
|
中山醫學大學附設醫院
|
|
99
|
TNF-α、TNF-α接受器與microRNA-146a基因多形性與僵直性脊椎炎發生之相關
|
共同主持人
|
500,000
|
中山醫學大學附設醫院
|
|
99
|
建立以醫院為基礎的僵直性脊椎炎病患世代，並且探討骨骼重塑與自體免疫耐受性的可能效應 (三年期計畫)
|
主持人
|
3,150,000
|
國家科學委員會
|
|
98
|
脂締素和腫瘤壞死因子-a基因多形性與代謝症候群發生之效應
|
共同主持人
|
500,000
|
中山醫學大學附設醫院
|
|
98
|
台灣鄉村居民砷及鉛暴露與血壓之相關：含錳超氧歧化酶MnSOD及核酸糖解酶OGG1基因的可能效應
|
共同主持人
|
270,000
|
中山醫學大學附設醫院
|
|
98
|
計畫性細胞死亡-1 (programmed cell death 1) 及其配位基基因多形性與僵直性脊椎炎之相關
|
共同主持人
|
270,000
|
中山醫學大學附設醫院
|
|
97
|
輪班工作與發炎基因、血管重塑基因、血管內皮基因之基因多形性影響台灣職業駕駛的脈波傳導速率之貢獻
|
共同主持人
|
270,000
|
中山醫學大學附設醫院
|
|
97
|
農藥暴露與粒線體DNA傷害
|
主持人
|
1,117,044
|
國家科學委員會
|
論文發表
|
年度
|
著作
|
期刊
屬性
|
期刊最佳
百分比
|
|
100
|
Wong RH, Wei JCC, Huang CH, Lee HS, Chiou SY, Lin SH, Cai YW, Hung PH, Wang MF, Yang SF, (2011), Assiociation of IL-12B genetic polymorphism with the susceptibility and disease severity of ankylosing spondylisis. J Rheumatol
|
SCI
|
37%
|
|
100
|
Huang JF, Wong RH, Chen CC, Mao IF, Huang CC, Chang WH, Wang L, (2011), Trajectory of depression symptoms and related factors in later life - a population based study. J Affect Disord. 133(3):499-508.
|
SCI
|
21%
|
|
100
|
Huang CH, Wong RH, Wei JCC, Tsay MD, Chen WC, Chen HY, Shih WT, Chiou SP, Tu YC, Lee HS, (2011), Effects of genetic polymorphisms of the programmed cell death 1 and its ligands on the development of ankylosing spondylitis. Rheumatology. 50(10):1809-13.
|
SCI
|
31%
|
|
100
|
Huang PL, Wang MF, Lee HS, Liu YJ, Chen CC, Chen SC, Lai JS, Wong RH, (2011), An OGG1 polymorphism is associated with mitochondrial DNA content in pesticide-exposed fruit growers. Toxicology; 287(1-3): 8-14.
|
SCI
|
18%
|
|
100
|
Chung TT, Pan MS, Kuo CL, Wong RH, Lin CW, Chen MK, Yang SF, (2011), Impact of RECK gene polymorphisms and environmental factors on oral cancer susceptibility and clinicopathologic characteristics in Taiwan. Carcinogenesis; 32(7): 1063-1068.
|
SCI
|
14%
|
|
100
|
Tang SC, Wu MF, Wong RH, Liu YF, Tang LC, Lai CH, Hsu CP, Ko JL, (2011), Epigenetic mechanisms for silence of Glutathione S-transferase M2 expression by hypermethylated Sp1 binding in lung cancer. Cancer; 117(14): 3209-3221.
|
SCI
|
15%
|
|
100
|
Wei JC, Yen JH, Juo SH, Chen WC, Wang YS, Chiu YC, Hsieh TJ, Guo YC, Huang CH, Wong RH, Wang HP, Tsai KL, Wu YC, Chang HW, Hsi E, Chang WP, Chang WC, (2011), Association of ORAI1 Haplotypes with the Risk of HLA-B27 Positive Ankylosing Spondylitis. PLoS One; 6(6): e20426.
|
SCI
|
13%
|
|
100
|
Ting H, Wong RH, Yang HJ, Lee SP, Lee SD, Wang L, (2011), Sleep disordered breathing, behavior, and academic performance in Taiwan schoolchildren. Sleep Breath; 15: 91-98.
|
SCI
|
58%
|
|
100
|
Wei JCC, Romero-Sánchez C, Tsou HK, Jan MS, Wong RH, Chiou SY, Londoño J, Valle-Oñate R, Howe HS, Yu D, Leung B, (2011), Serum monocyte chemotactic protein-1 concentrations distinguish patients with ankylosing spondylitis from patients with mechanical low back pain. J Spin Disord Tech; 24(3): 202-207.
|
SCI
|
47%
|
|
100
|
Huang CH, Wong RH, Wei JCC, Hung PS, Shiu LJ, Tsay MD, Lee HS, (2011), Osteoprotegerin genetic polymorphisms and age of symptom onset in ankylosing spondylitis. Rheumatology; 50(2): 359-365.
|
SCI
|
31%
|
|
100
|
Hsieh HI, Chen PC, Wong RH, Du CL, Chang YY, Wang JD, Cheng TJ, (2011), Mortality from liver cancer and leukemia among polyvinyl chloride workers in Taiwan: an updated study. Occup Environ Med; 68(2): 120-125.
|
SCI
|
13%
|
|
99
|
Kuo Chou TN, Chao WN, Yang C, Wong RH, Ueng KC, Chen SC, (2010), Predictors of mortality in skin and soft-tissue infections caused by Vibrio vulnificus. World J Surg; 34(7): 1669-1675.
|
SCI
|
18%
|
|
99
|
Kuo Chou TN, Li YS, Lue KH, Liao CF, Lin CY, Tzeng PR, Wong RH, (2010), Genetic polymorphism of manganese superoxide dismutase is associatedwith childhood asthma. J Asthma; 47(5): 532-538. SCI
|
SCI
|
63%
|
|
99
|
Kuo Chou TN, Lee YT, LaiYY, Chao WN, Yang C, Chen CC, Wang PH, Lin DB, Wong RH, Chen SC, (2010), Prognostic factors for primary septicemia and wound infection caused by Vibro vulnficus. Am J Emerg Med; 28(4): 424-431.
|
SCI
|
30%
|
|
99
|
Chien WP, Wong RH, Cheng YW, Chen CY, Lee H, (2010), Associations of MDM2 SNP309, transcriptional activity, mRNA expression, and survival in Stage I non-small cell lung cancer patients with tumors containing wild-type p53. Ann Surg Oncol; 17(4): 1194-1202.
|
SCI
|
4%
|
|
99
|
Tang SC, Sheu GT, Wong RH, Huang CY, Weng MW, Lee LW, Hsu CP, Ko JL, (2010), Expression of glutathione S-transferase M2 in stage I/II non-small cell lung cancer and alleviation of DNA damage exposure to benzo[a]pyrene. Toxicol Lett; 192(3): 316-323.
|
SCI
|
20%
|
|
99
|
Chen CC, Shiu LJ, Li YL, Tung KY, Chan KY, Yeh CJ, Chen SC, Wong RH, (2010), Shift work and arteriosclerosis risk in professional bus drivers. Ann Epidemiol; 20(1): 60-66.
|
SCI
|
14%
|
|
98
|
Wei JCC, Lee HS, Chen WC, Shiu LJ, Yang SF, Wong RH, (2009), Genetic polymorphisms of the matrix metalloproteinase-3 (MMP-3) and tissue inhibitors of matrix metalloproteinases-1 (TIMP-1) modulate the development of ankylosing spondylitis. Ann Rheum Dis; 68(11): 1781-1786.
|
SCI
|
3%
|
|
98
|
Chang SH, Wang KS, Chang HF, Ni WW, Wu BJ, Wong RH, Lee HS, (2009), Comparison of source identification of metals in road-dust and soil. Soil Sediment Contam; 18: 669-683.
|
SCI
|
89%
|
|
98
|
Chien WP, Wong RH, Wu TC, Cheng YW, Chen CY, Lee H, (2009), Potential increase in the prognostic value of P53 mutation by Pro72 allele in stage I non-small cell lung cancer. Ann Surg Oncol; 16(7): 1918-1924.
|
SCI
|
4%
|
|
98
|
Lin IH, Chao MR, Hu CW, Ho ML, Huang JY, Lee HS, Chen CC, Wong RH, (2009), Modification of urinary N7-methylguanine excretion in smokers by glutathione-S-transferase M1 polymorphism. Toxicology; 260(1-3): 1-6.
|
SCI
|
18%
|
|
98
|
Huang CC, Chien WP, Wong RH, Chen MC, Lee H, (2009), NAT2 fast acetylator genotype and MGMT promoter methylation may contribute to gender difference in K-RAS mutation occurrence in Taiwanese colorectal cancer. Environ Mol Mutagen; 50(2): 127-133.
|
SCI
|
10%
|
|
98
|
Chao MR, Chang YZ, Wong RH, Hu CW, (2009), Time course evaluation of N-nitrosodialkylamines-induced DNA alkylation and oxidation in liver of mosquito fish. Mutat Res; 660(1-2): 33-39.
|
SCI
|
2%
|
|
97
|
Wong RH, Chang SY, Ho SW, Huang PL, Liu YJ, Chen YC, Yeh YH, Lee HS, (2008), Polymorphisms in metabolic GSTP1 and DNA-repair XRCC1 genes with an increased risk of DNA damage in pesticide-exposed fruit growers. Mutat Res; 654(2): 168-175.
|
SCI
|
2%
|
|
97
|
Wong RH, Hu CW, Yeh CY, Chao MR, Chen CC, Huang JH, Chang SH, Lee SI, Lee HS, (2008), Sulfotransferase 1A1 and glutathione S-transferase P1 genetic polymorphisms modulate the levels of urinary 8-hydroxy-2’-deoxyguanosine in betel quid chewers. Arch Toxicol; 82(5): 313-321.
|
SCI
|
9%
|
|
97
|
Wei JCC, Su YC, Chang HC, Jan MS, Wong RH, Chou CT, (2008), Patient attitudes toward western medicine and the future of Chinese medicine for spondyloarthritis. Curr Rheumatol Rev; 4(2): 120-123.
|
SCI
|
|
|
97
|
Chen SC, Wong RH, Shiu LJ, Chiou MC, Lee H. 2008/1. Exposure to mosquito coil smoke may be a risk factor for lung cancer in Taiwan. J Epidemiol; 18(1): 19-25.
|
SCI
|
35%
|
|
